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10.1016/j.biopsych.2019.02.008 Biol

In animal studies, Ozempic or Trulicity caused thyroid C-cell tumors, including MTC (medullary thyroid carcinoma)

For repeat dose toxicity, concordance of organ level findings ranged from 38.5% to 90%, with study metadata explaining at most 60 to 70% of the total variance

Excess weight accelerates cartilage breakdown through increased mechanical stress and contributes to a pro-inflammatory state that may further damage joint structures