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Further, liraglutide protects against vascular oxidative stress via attenuating eNOS (endothelial NO synthase) s-glutathionylation (a hallmark of eNOS uncoupling) and increasing NO bioavailability [15]

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Clinical eligibility for brand-name GLP-1 medications generally requires an adult patient to have a body mass index (BMI) of 30 or greater, or a BMI of 27 or higher paired with a weight-related health condition such as high blood pressure