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UK product information includes warnings about thyroid C-cell tumours observed in rodent studies, though this is not a formal contraindication in the UK as it is in some other countries

Annu Rev Biochem 52:711760 Njalsson R, Norgren S, Larsson A, Huang CS, Anderson ME, Luo JL (2001) Cooperative binding of gamma-glutamyl substrate to human glutathione synthetase

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