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In addition, we did not find a significant non-linear relationship between dose (g/day) (coefficients = 8.54, p = 0.054) and changes in HOMA-IR, although there was a significant non-linear relationship between duration of the intervention (coefficients = 0.22, p = 0.015) and changes in HOMA-IR
Similarly, physiological effects observed in rodents rarely map perfectly onto humans due to vast differences in dosing, half-life, and tissue exposure
The medication has heartburn or acid reflux as a possible side effect in its prescribing information
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