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In many places, it exists in a regulatory gray area, being available for research purposes but not approved for human consumption
A randomized, double-blind, placebo-controlled clinical trial conducted in 30 healthy Filipino women aged 3050 years has provided some evidence favouring the efficacy of topical 2% GSSG lotion in temporary skin lightening
Thus, there is a need for larger studies to fully address this issue
Research in this area continues
These findings position mTORC1 upstream of ISR signaling in this context
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