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Conclusion Our study reveals that the activation of NLRP3 inflammasome caused by mitophagy dysfunction plays an important role in cardiac hypertrophy induced by pressure overload, and semaglutide ameliorates the cardiac hypertrophy by improving cardiac mitophagy to suppress the activation of NLRP3 inflammasome
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N Engl J Med 2015;373:2117-28.ArticlePubMed 37
Other symptoms are severe jaundice, diarrhoea, fever, pruritus, and hepatosplenomegaly
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