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Topiramate is an anticonvulsant with appetite-affecting properties, sometimes included in weight loss medication combinations
Even though the PLC/PKC signaling pathway has been shown to be involved in GLP-1-induced insulin secretion in mouse pancreatic cells [56], this signaling pathway was unlikely involved in the effect of exendin-4 on GABA currents in GCs, due to the persistence of this effect when PI-PLC or PC-PLC was blocked (Fig
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