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The medication is also prescribed off-label for weight loss in individuals without diabetes
Lancet Diabetes Endocrinol 2019;7:606-17.ArticlePubMed 45
Retatrutide does it indirectly, by stripping out the body fat that produces inflammatory cytokines
What Retatrutide Is: A Triple-Receptor Agonist Built for Weight and Glucose Retatrutide is a once-weekly, subcutaneously administered synthetic peptide engineered to activate three distinct receptors at once: the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR)
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