However, some people may experience gastrointestinal side effects like nausea and vomiting, which can sometimes mimic symptoms of food poisoning
The same 2025 trial reports that long-term comparative effectiveness of once-weekly semaglutide versus alternative treatments in a real-world US adult population with type 2 diabetes: a randomized pragmatic clinical trial, "Patients on semaglutide experienced an average weight loss of 5.6 kg, compared to 2.3 kg with other treatments.", showing a measurable weight advantage that often drives secondary hormonal and quality of life effects
Sources Medicines and Healthcare Products Regulatory Agency
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However, their clinical application necessitates a comprehensive assessment of each patients unique physiological characteristics