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however we cannot establish causality based on these retrospective results and further prospective investigations are needed. In the second study, researchers focused on examining how GLP-1 use might impact the risk of developing osteoporosis, gout, or osteomalacia (bone softening) in people with type 2 diabetes and obesity

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Schoretsanitis and Gastaldon found that patients who are co-prescribed antidepressants and the GLP-1 agonist semaglutide may be at risk of developing suicidal ideation