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Tew KD et al

He has successfully supported over 30 new drug IND applications globally

Chronic inflammation, endoplasmic reticular stress, and OxS caused by glycolipid toxicity are all related to the progression of -cell failure [29, 30]

It has also been observed a correlation between high levels of GSTP1-1 in the brain and medical intractability, suggesting that the enzyme may contribute to resistance to antiepileptic drug treatment 62

Under these conditions, this imbalance leads to intense competition for available chaperones, impairing their ability to assist in the folding of other substrates, including newly synthesized and damaged proteins