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Branded tirzepatide is FDA-approved for chronic weight management and for type 2 diabetes

Hyperglycemia results in the storage of metabolic substrates, causing the accumulation of glycolytic intermediates and the formation of mitochondrial ROS (mtROS) from the electron transport chain (ETC), ultimately inducing mitochondrial dysfunction and energy metabolism imbalance[112, 113]

2021;10: e019463

, leading to an uptick in patients getting diagnosed and starting prescriptions for other conditions, according to a new analysis by health-data firm Truveta

No major medical society or regulatory body has endorsed this practice