Clambey ET, McNamee EN, Westrich JA, Glover LE, Campbell EL, Jedlicka P, et al
Methionine aids in fat processing and cholesterol reduction Inositol supports fat metabolism and brain function Choline contributes to energy generation and neural communication B12 enhances various metabolic processes and overall well-being
During development and progression of atherosclerosis, Nrf2 signaling modulates many physiological and pathophysiological processes, like regulation of lipid homeostasis, CD36 gene expression regulation, foam cell formation, macrophage polarization, immunity regulation (Th2 differentiation and inhibition of pro-inflammatory gene expression through NFB down-regulation), redox regulation and inflammation, improvement of endothelial dysfunction, as well as GSH synthesis and utilization (234245)
Berberine works primarily by activating an enzyme called AMP-activated protein kinase (AMPK), which acts like a sensor inside cells for low energy (ATP) levels
2a, energy profile: Fig
