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January 6, 2026 3,097 Total MDL Cases As of January 2026, the GLP-1 weight loss drug MDL includes 3,063 pending cases

The difference in results between local and non-local administration remains unclear from available research

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Evidence revealed that endogenous and exogenous IGF-1 administration protects against the onset and progression of diabetic cardiomyopathy [278, 279]

Contraindications include: Active seizure disorder or history of seizures Anorexia nervosa or bulimia nervosa (current or past) Abrupt alcohol withdrawal or sedative withdrawal Concurrent use of MAOIs These contraindications apply regardless of whether GLP-1 is being used