Non-specific tissue loss (muscle, bone, hair, etc) is well documented with any kind of caloric restriction and correlates with weight lost so liraglutide data likely underestimate the effects of semaglutide and tirzepatide as you point out
However, the mechanism of cell type-specific ferroptosis sensitivity remains unclear, and the inherent susceptibility to ferroptosis of untreated cancers varies significantly by organ system 39
That makes room for the healthiest, most viable cells
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While they endow CB with advantages as a chassis bacterium for engineering modification and promising prospects in cancer therapy, they also restrict the application of ECB