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However, some clinicians suggest reducing to 50% of your normal dose as a middle-ground approach if you're moderately ill but able to eat light meals

If its nearly time for the next days dose, skip the missed one

Lancet 397(10278):971984 Garvey WT, Frias JP, Jastreboff AM, le Roux CW, Sattar N, Aizenberg D et al (2023) Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

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If confirmed, this could eventually be due to small differences in bioavailability, distribution or elimination of the peptide-antibody fusion compared to conventional mAbs