Although lifestyle changes are the first line of treatment for obesity, even the most rigorous lifestyle changes typically only produce a 510% weight loss and maintaining weight over time is difficult due to compensatory physiological processes that increase appetite and decrease energy expenditure [134]
(2) K Raun, B S Hansen, N L Johansen, H Thgersen, et al (1998) Ipamorelin, the first selective growth hormone secretagogue European Journal of Endocrinology, 1998 Nov, Volume 139 (Issue 5), Pages 552-61
reassessment should occur after 812 weeks with clinical guidance
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When you eat, your food stimulates your gut to release the GLP-1 hormone