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Caution is advised in patients with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
First of all, apparently, it works in the reverse: GLP-1 receptor inhibition can result in weight loss (in mice), so, thats pretty weird
This is an important treatment aspect, as weight reduction most likely plays an important role in the prevention and reduced progression of CKD, an association demonstrated in people with macroalbuminuria having undergone bariatric surgery [115]
TRANSCEND-T2D-1 randomized 537 patients with type 2 diabetes and inadequate glycemic control in a 1:1:1:1 ratio to receive one of three retatrutide doses (4, 9, or 12 mg) or placebo
Proceedings of the American Thoracic Society
