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Statistical significance was determined by a two-sided unpaired t-test compared to non-cancer samples ( a , b , c ), or untreated cells ( f )

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Timing differences can confound time-dependent outcomes in sensitive assays and analytical comparisons

Semaglutide activates GLP-1 receptors in the brain to reduce hunger signals and increase feelings of fullness, slows gastric emptying to prolong satiety, and improves insulin sensitivity and blood sugar regulation