Product Facts Supplement Facts Serving Size 1 Veg Capsule Servings Per Container 60 **Daily Value not established Other Ingredients: Hypromellose (cellulose capsule), Microcrystalline Cellulose, Ascorbyl Palmitate and Silicone Dioxide
Research Insight A research insight from Ipamorelin 10MG shows its ability to stimulate GH release selectively with minimal off-target effects
Arterburn DE, Johnson E, Coleman KJ, Herrinton LJ, Courcoulas AP, Fisher D, et al
Peptide clearance does not scale identically across species, and the animal work used anesthetized preparations and doses far above the human protocol
Benefits (Research Focus) IGF-1 receptor activation studied for selective high-affinity agonism of the IGF-1 receptor PI3K/Akt/mTOR signaling investigated for downstream activation of cellular growth and protein synthesis pathways Reduced IGFBP binding explored for the Arg substitution that decreases IGF-binding protein affinity Extended half-life examined for ~20-30 hour bioactivity window compared to ~15 minutes for native IGF-1 Skeletal muscle research researched for satellite cell activation and protein synthesis endpoints in preclinical models What Researchers Look At IGF-1R binding affinity and downstream phosphorylation cascades (IRS-1, Akt, S6K) PI3K/Akt/mTOR pathway activation in muscle and metabolic cell models IGFBP-3 binding affinity and free fraction pharmacokinetics Skeletal muscle protein synthesis and satellite cell activation endpoints Comparative bioactivity versus native IGF-1 and other IGF-1 analogs in cell-culture systems Quick Specs Form: Lyophilized white powder Net Peptide Content: 1 mg per vial Quantity: 1 vial Appearance: White to off-white lyophilizate Reconstitution: Bacteriostatic or sterile water (added by the end researcher) Purity: 99% by HPLC Identity: MS-verified (per COA) Storage: Protect from light Identity Basics Compound: IGF-1 LR3 (Long [Arg] Insulin-like Growth Factor-1) Synonyms: Long R3 IGF-1
