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Genetic and Biomarker Context in Hepatic Metabolism Individual responses to glutathione and milk thistle supplementation are influenced by genetic variants in Phase I and Phase II detoxification enzymes, antioxidant pathways, and liver function markers

Int J Clin Exp Pathol (2018) 11(3):177783

10.1128/IAI.00136-08

Abstract Tumor-associated macrophages (TAMs) are central regulators of the metabolic and immunological landscape of solid tumors and are increasingly recognized as key determinants of cancer-cell susceptibility to ferroptosis

Because one assumes that water is ubiquitous one does not need to account for protons except for knowing the prevailing pH which depicts the tendency to give or receive protons