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By being custom-made, "[compounded drugs] can be risky for patients, as unapproved versions do not undergo FDA's review for safety, effectiveness and quality before they are marketed," the issue said
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For example, someone with cardiovascular symptoms wouldnt meet the criteria unless they also had gastrointestinal or dermatological symptoms.[ref] One form of MCAS, now called idiopathic anaphylaxis , involves sudden, often random-seeming episodes of throat swelling, itching, wheezing, shortness of breath, stomach pain, nausea, vomiting, diarrhea, and a drop in blood pressure
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