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When you do intense exercise, you release endotoxin from your gut
However, as explained by the Alzheimers Drug Discovery Foundation in 2024, while urolithin A does have an impressive safety profile, its long-term safety has yet to be established.4 Also, while rare, some people can be allergic to pomegranates, which are rich in the polyphenols that are metabolized into urolithin A.21 This doesnt necessarily mean that those with pomegranate allergies will have a reaction to urolithin A supplements, but it could be something to keep in mind
2009 MayJun
Researchers conducting in vitro or cell-based assays in particular should confirm low endotoxin levels in any BPC-157 peptide preparation before use, as cellular assay systems are particularly sensitive to lipopolysaccharide contamination artifacts
