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Unlike single- or dual-receptor peptides, Retatrutide simultaneously targets three key metabolic receptors: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)
Metabolic fate of dietary carnitine in humans
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The root growth of mutants affected in these three MRPs was not distinguishable from that of WT upon AITC treatment
First, we should identify populations that are suitable or unsuitable for GLP-1RA-centric combination therapy
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