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The scientific interest in this combination stems from the possibility of observing, in controlled experimental models, complementary biological pathways involved in cellular migration, stress response, actin dynamics, and structural repair processes

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2008 Jan;134(1):166-178

Moreover, ALA has been demonstrated to regulate the neuropathology of BDNF in mice model (Vasconcelos et al., 2015

Conclusion The use of SGLTis and GLP-1 RAs represents a paradigm shift in the management of HF, moving beyond their traditional role as drugs for diabetes