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This medication is not recommended for people who: Have a history of pancreatitis Have a history of gastroparesis (paralysis of the stomach) Have medullary thyroid cancer or multiple endocrine neoplasia type 2 or a family history of these conditions Are on dialysis (as the safety of using GLP-1 agonists in this situation hasn't been proven) In addition, people with impaired kidney function due to diabetes who have a GFR (glomerular filtration rate) of 30 or less should not use Byetta but may be able to take another GLP-1 receptor agonist
(Cochrane Metabolic and Endocrine Disorders Group) (June 2020)
10.1177/0960327112438287 Hum Exp Toxicol
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All pharmacodynamic evaluations were performed after 12 weeks of treatment (including dose escalation) at steady state with semaglutide 1 mg
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