But we know that in people with Type 2 diabetes that sense is often impaired and if you give someone GLP-1 you can switch off the appetite to some extent and achieve some weight reduction
Plant Signal
He held a master's Certificate, and had been navigating officer of some of the finest steamers, was a member of the Meteorological Society of London, and was qualified to undertake any kind of marine surveying. Theodore F Bevan, of the RGSA, wrote about that expedition and the subsequent gold rush in his book Toil, travel and discovery in British New Guinea
Instead of following a precise program, you are essentially taking a mystery dose
Signs you're ready to move to the next dose: GI symptoms (nausea, vomiting, diarrhea) have resolved or are minimal for at least 7 consecutive days Appetite suppression remains noticeable but you sense a plateau effect developing at the current dose You have completed at least 4 full weeks at the current dose level You have no significant intercurrent illness that might confuse attribution of new symptoms Signs to wait: Ongoing nausea or vomiting, even if mild, at the end of the current dose phase A recent GI illness (unrelated to the medication) that makes it hard to attribute current symptoms A major life stressor or schedule disruption that might amplify side effects Fewer than 4 weeks at the current dose, regardless of how you feel When in doubt, an additional week at the current dose costs very little
