Patients should contact their GP or diabetes specialist nurse if they experience: Severe or persistent vomiting that prevents adequate fluid or food intake, as this increases the risk of dehydration and hypoglycaemia Severe abdominal pain , particularly if constant or radiating to the back, which could indicate pancreatitisa rare but serious adverse effect of GLP-1 receptor agonists Sudden pain in the right upper abdomen, fever or jaundice , which may indicate gallbladder problems (cholelithiasis or cholecystitis) Blood in stools or black, tarry stools Unexplained weight loss beyond what is expected from the medication's therapeutic effect Signs of dehydration , including reduced urine output, dizziness, or confusion Persistent diarrhoea lasting more than a few days Symptoms that significantly impair quality of life or prevent adherence to the medication regimen Pancreatitis is a particular concern with semaglutide, though it remains uncommon

He did so with his doctor's cautious blessing and despite the various unknowns like what's in the drug, exactly, or how he might react to it
He was president of Sony Pictures Motion Picture Group
10.7759/cureus.50351 232 WangY.GaoW.ShiX.DingJ.LiuW.HeH.et al (2017)
Does Tirzepatide work better than Semaglutide GLP-1