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J Pharmacol Pharmacother (2013) 4(3):17686.10.4103/0976-500X.114596 6 NasrallahHAMeyerJMGoffDCMcEvoyJPDavisSMStroupTSet alLow rates of treatment for hypertension, dyslipidemia and diabetes in schizophrenia: data from the CATIE schizophrenia trial sample at baseline

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These medications work by reducing hunger, slowing stomach emptying, and altering food preferences, which can lead to lower calorie intake and, in some cases, unintended side effects such as nausea, constipation, and loss of lean muscle mass

We observed a modest but significant correlation between decreases in CRP and reductions in troponin with tirzepatide, suggesting that anti-inflammatory effects may contribute to cardiac benefits