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Mechanistically, TMAO disrupts myocardial calcium homeostasis through two distinct pathways: direct elevation of intracellular Ca 2+ concentration and promotion of SERCA2a (sarco/endoplasmic reticulum Ca 2+ -ATPase) autophagic degradation, which attenuates sarcoplasmic reticulum Ca 2+ reuptake capacity (Lei et al., 2025)
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* Additionally, I thought it interesting and of note that one major study on the DR7 bacteria started during the year-end period of 2017 in East Peninsular Malaysia, which also corresponded to the period of annual monsoon season, for 12 weeks, which coincided with the aftermath of a flood
Phytochemicals for drug discovery in alzheimers disease: in Silico advances
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