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3,11,12,30 DPP-4 inhibitors have not been shown to cause weight gain or hypoglycemia unless used in combination with other antihyperglycemic agents, such as insulin or sulfonylureas
Eur J Clin Pharmacol 1998;54:503-8
L., & Sahebkar, A
GLP-1 and Longevity: Beyond Weight Loss Recent animal studies show GLP-1 agonists may extend lifespan in mice with obesity and metabolic disease (Zhang et al., 2021)
Resveratrol not only induces SIRT1 activation to modulate insulin signaling, but also extends lifespan and prevents age-related diseases in part by regulating NF-B signaling and MAPK (Gao and Ye, 2008)
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