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GLP-1 receptor agonists (semaglutide, dulaglutide, liraglutide) work by enhancing insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite

On top of these administrative hurdles, drug shortages have plagued the market, making it difficult for patients to start or continue treatment

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Age, weight, and comorbid conditions impact pharmaceutical pharmacokinetics, glycemic management, and operative risk