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Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

Any insulin changes should be made carefully with guidance from a clinician to avoid hypoglycemia or ketosis

It is important to recognize that patients initiating tirzepatide often have underlying conditionssuch as obesity, type 2 diabetes, cardiovascular disease, or obstructive sleep apneathat independently increase the risk of respiratory symptoms

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