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OTC alternatives do not address these underlying insulin and glucose dysregulation pathways with pharmacological precision, limiting their utility for metabolically complex cases

Convincing evidence that GLP-1R stimulating drugs are associated with anti-inflammatory, neurotrophic, and neuroprotective properties in preclinical models of NDD has led to trials of these drugs in the NDD clinic

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While semaglutide was primarily designed as a longer acting compound compared with liraglutide (53), it has been shown to provide benefits beyond its protraction

(2002) 'Heat stroke', New England Journal of Medicine, 346(25), pp