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What the clinical data say, in brief Barrier and texture: Nicotinamide improves barrier metrics, elasticity, and hydration in randomized controlled studies

This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize

This mimics the bodys innate secretion patterns, thereby preserving regulatory feedback mechanisms between GH and insulin-like growth factor 1 (IGF-1)

Second, we assessed each drug in expanded populations reflective of patients routinely seen in clinical practice

DAscanio AM, Mullally JA, Frishman WH