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After this period, the mice on the HFD were randomly divided into two groups for an additional 4 weeks: one group received semaglutide treatment (HFD SEMA) and the other group received a saline solution (HFD SAL)
The difference lies in the base peptide
Liraglutide and exendin-4 are initially antidiabetic drugs but can affect tumorigenesis, suggesting GLP-1R agonists as a potential treatment for different cancers as found in vivo (Table 2)
The substantial 20mg concentration is exceptionally well-suited for extended research protocols, granular dose-response studies, and complex comparative investigations alongside other incretin-based peptides, providing domestic researchers with unparalleled experimental flexibility
