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(C) Quantification of oxygen consumption rate (OCR) to assess basal respiration, ATP-linked respiration, maximal respiration, and spare respiratory capacity in TD-N, ASD-N, and ASD-DM NPCs

Primarily summarized into 3 main MOA: MOA: Increases Insulin release/sensitivity, decreases glucagon release MOA: Slows gastric emptying (gastric peristalsis) MOA: Appetite Suppression Patho 101: Plasma glucose is maintained by a tug-of-war between the hypoglycemic effect of insulin and the hyperglycaemic effect of glucagon

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The absence of human trials means safety is uncharacterised