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In db/db mice, administration of M-920, a caspase inhibitor, reduced renal CASP1, IL-1, IL-18, and NLRP3 inflammasome activation, leading to amelioration of albuminuria and renal ECM accumulation (198)
More receptors = stronger signal = more appetite suppression from the same dose
Oct 6 : Arcutis Biotherapeutics is adding another indication for its psoriasis cream, Zoryve, after the FDA approved the companys supplemental New Drug Application (sNDA) to expand the treatment for children ages 6 to 11
The evidence spans liver protection, kidney protection, and systemic anti-fibrotic activity
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