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Among these ERAD targets are p53, peroxisome proliferator-activated receptor gamma coactivator 1- (PGC-1), and N 6 -adenosine methyltransferase-14 (METTL14)

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Given these anti-inflammatory effects, there is speculation that GLP-1 medicines could impair host immune defenses

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Bibcode:2013ApEnM..79..722Y