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Bradshaw WG, Baum MJ, Awh CC
Dark under-eye circles can be caused by various factors, including genetics, thinning skin due to aging, lack of sleep, dehydration, allergies, pigmentation irregularities, and lifestyle habits like smoking or excessive alcohol consumption
These findings offer us the opportunity to continuously and directly analyze the evolution of Neisseria pathogenicity, and on the other hand, suggest the need to activate continuous surveillance also for Neisseria not normally associated with human colonization, in order to better define their pathogenic and evolutionary potential
This mutation results in the change of proline at amino acid position 46 to a serine and this mutation is designated P46S (p.P46S)
