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These conditions spontaneously generate activated myofibroblastic VICs (aVICs), characterized by high expression levels of alpha smooth muscle actin (SMA) and other myofibroblastic markers 38

So, for older adults, the muscle mass lost on a GLP-1 might limit physical function

It is important to note that there is no established link between GLP-1 receptor agonists and worsening of autoimmune thyroid disease in humans

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