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Gentamicin-induced nephrotoxicity: A mechanistic approach

Prospective Studies Collaboration, Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, et al

The study included health data for 7,044 adults admitted to a hospital for acute ischemic stroke between January 2000 and June 2022 Average age was 72 years, 52% male, 94% were white, 1.5% as Black adults, 1.5% as Asian adults and 3% identified as adults of "other" race

Despite strong clinical evidence supporting the effectiveness of GLP-1 therapies for weight loss, coverage remains inconsistent and often restrictive

The half-life of tirzepatide is approximately five days, allowing weekly dosing to maintain therapeutic plasma levels throughout the dosing interval