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This metabolic improvement precedes visible fat loss but indicates the medication is engaging its mechanisms properly
Phentermine (and Qsymia, which contains phentermine) should never be taken within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) class of drugs because of the risk of hypertensive crisis (a sudden, severe increase in blood pressure)
The FDA resolved that shortage in 2024, narrowing but not eliminating the pathway
Bioavailability data: A study by Witschi et al
doi: 10.1016/j.plaphy.2020.05.003 69 CrozierA.JaganathI
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