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Following BPD, the 24-hour mean circulating leptin concentration decreased from 51.94 9.21 to 15.04 4.80 ng/ml, while insulin levels dropped from 54.84 6.51 to 10.03 1.48 ng/ml
Incretin-based multi-agonists, such as tirzepatide and retatrutide, target two or more receptors among GLP-1, GIP, and GCGR to enhance insulin secretion, improve fat metabolism, and increase energy expenditureultimately achieving greater weight loss and metabolic improvement
Therefore, supplementation with exogenous antioxidants represents a useful adjunct option in the treatment of psoriasis
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