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Schedule (Once Weekly Injection) Upper limit: 12 mg per week is the highest dose used in the major published clinical trials (Phase 2 obesity, Phase 2 type 2 diabetes, and the Phase 3 TRIUMPH-4 and TRANSCEND-T2D-1 studies)

18 A study in 2003 compared oral versus sublingual cyano-B12 (500 g per day for 8 weeks), and found that both increased B12 levels significantly without a significant difference between the two

National Institutes of Health

Contamination can lead to adverse effects such as headaches, dizziness, nausea, vomiting or other more serious effects depending on the contaminated substance

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