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doi: 10.3390/microorganisms11010208 146 KoolhaasJ
Type II: This type is mainly found in cartilage and connective tissue
Xanthine oxidase (XO), which participates in purine metabolism, is another key enzymatic source of ROS, producing both superoxide and HO during the conversion of hypoxanthine to xanthine and xanthine to uric acid 50
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