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The inability to utilize fat for energy during stress or fasting can trigger acute metabolic decompensations early in life

Although a significantly elevated renal CAT activity in 6- and 16-week old, 22 and older SHR 8, 23 has been reported before, this is the first time that altered renal CAT expression and activity has been reported in pre-hypertensive SHR

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Progressive improvement over subsequent weeks often allows gradual return to running activities that had been impossible