The disc relies on diffusion, a slow process where nutrients seep in from surrounding tissues through the endplates
Among these, TNF- is highlighted as a critical driver, with elevated levels in serum and peritoneal fluid of patients with active lesions, and its altered balance with Th1/Th2 cytokines linked to embryo toxicity and endometrial dysfunction ( Immune checkpoint molecules, which regulate immune tolerance, are also dysregulated in endometriosis
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Muscle matters