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For most individuals, this phase marks the period when consistent and long-term changes in eating habits are most evident

The psychological burden of carrying excess weight, particularly in a culture that conflates thinness with desirability, can suppress sexual desire as effectively as any hormonal imbalance

[152] In November 2025, the United States President Donald Trump announced a deal with NovoNordisk to lower the costs of Ozempic, including monthly prices of about $245 for injectables and $149 for some oral versions for people on Medicare and Medicaid and for those who use his TrumpRx platform

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They are often prescribed when lifestyle interventions and first-line therapies alone are insufficient