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Yes, it is generally considered safe
Additionally, the cyclic trisulfide structure of LASSS, as opposed to the linear trisulfides such as GSSSG and cysteine trisulfide (Cys-SSS-Cys), could guarantee the unique reactivity of LASSS (see again Figure 1a for chemical structures)
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According to UK regulatory data, skin reactions including rash are classified as uncommon, potentially affecting up to 1 in 100 people
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